Science
When microbial DNA is scarce, new profiling method helps separate genuine signals from contamination
In acute, life-threatening infections, rapidly characterizing the microorganisms in a patient sample can help guide diagnosis and treatment.
AI Summary
In acute, life‑threatening infections, rapid identification of the microbes present in patient samples can inform diagnosis and treatment decisions. Taxonomic profilers are computational tools that analyze metagenomic sequencing data by matching it to reference microbial genomes. These methods are still being refined and are not yet widely adopted. Existing profilers can generate false‑positive detections and inaccurate estimates of microbial abundance.
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