Science · 3 views
Molecular snapshots reveal how bacteria assemble outer membrane proteins
These rearrangements of the SurA Core domain mediated by the SurA P1 and P2 domains enable SurA to bind unfolded outer membrane proteins and move them toward BAM.
AI Summary
Researchers captured molecular snapshots showing how Gram‑negative bacteria assemble proteins in their outer membrane, a structure that protects the cells and contributes to antibiotic resistance. The study visualizes the step‑by‑step process of protein insertion into the membrane, providing insight into the mechanisms behind the barrier’s formation. This detailed view could inform future strategies to target the outer membrane in drug‑resistant infections.
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