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Lab-designed molecule reduces amyloid beta, the protein linked to Alzheimer's disease, in mice
A research team led by the Molecular and Cellular Neurobiotechnology group at the Institute for Bioengineering of Catalonia (IBEC), in collaboration with Míriam Royo's laboratory at the Institute for Advanced Chemistry of Catalonia…
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A research team led by the Molecular and Cellular Neurobiotechnology group at the Institute for Bioengineering of Catalonia, working with Míriam Royo’s laboratory at the Institute for Advanced Chemistry of Catalonia, the University of Barcelona and the Institute for Research in Biomedicine, has identified a synthetic peptide that lowers production of amyloid‑beta, the protein that accumulates in Alzheimer’s disease. The peptide’s effects were demonstrated in cultured neurons and in a mouse model of the disease. The findings were published in the journal Bioorganic Chemistry.
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