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How mitochondria keep protein production moving
Researchers at Karolinska Institutet have discovered how a protein called TACO1 helps mitochondria produce proteins when the process encounters difficult sequences.
AI Summary
Researchers at Karolinska Institutet found that the protein TACO1 assists mitochondria in synthesizing proteins when ribosomes encounter challenging amino‑acid sequences. The study, published in *Nature Communications*, shows how TACO1 helps maintain efficient translation by the mitochondrial ribosomes, or mitoribosomes. This mechanism is disrupted in certain mitochondrial diseases, suggesting a link between TACO1 function and disease pathology. The work adds detail to how mitochondria produce the small but essential protein set required for cellular energy production.
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