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Week 2 NFL odds, picks, predictions: Computer model backs Seahawks and Buccaneers
Even those not on the West Coast could have a little more interest in making Week 2 NFL picks on either the Rams or 49ers. How those teams respond after playing in Australia last week is something that will be highly observed.
AI Summary
The Week 2 NFL schedule features the San Francisco 49ers hosting Miami and the Los Angeles Rams hosting the New York Giants. The 49ers are 12.5‑point favorites, the largest spread of the season, while the Rams give the Giants 7 points. Both games are among six matchups with a line of at least a touchdown, reflecting the impact of Week 1 results. The 49ers and Rams also have back‑to‑back primetime appearances. SportsLine’s computer model provides betting advice and predictions for these games.
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