AI Summary

Researchers led by Prof. Mareike Albert at TU Dresden used stem‑cell‑derived brain organoids to compare early brain development in humans, chimpanzees and gorillas. They discovered that human organoids exhibit more active genetic switches, boosting expression of genes that promote branching of neural precursor cells. This increased branching is associated with the production of more neurons, offering a mechanistic explanation for the larger human brain relative to great apes. The findings appear in Nature Communications.

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