AI Summary

Researchers at the Nano Life Science Institute, Kanazawa University, used high‑speed atomic force microscopy to watch microtubules in real time. They found that tiny structural defects can develop along the microtubule shaft and trigger collapse, even when the drug paclitaxel is present. This challenges the long‑held belief that microtubule breakdown starts mainly at the ends. The study, published in ACS Nano, provides new insight into how microtubule structure may affect cancer‑drug responses.

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