Summary

Cognition often deteriorates when the brain's main blood vessels are clogged, but a Columbia-led study published in JAMA shows that cognition cannot be improved by opening the blockages with stenting or surgery. "We had hoped that improving blood flow in the brain in this way would improve cognition—and there were tantalizing clues from animal studies and case series that it would," says study leader Randolph Marshall, M.D., the Elisabeth K. Harris Professor of Neurology at Columbia University Vagelos College of Physicians and Surgeons.

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