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Turning scar-forming cells into neurons helps restore movement after spinal cord injury

What if cells that form scars after a spinal cord injury could become part of the repair process?

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Researchers created a genetic system that reprograms scar‑forming cells in the spinal cord into neurons, leading to improved movement in mice and rats with spinal cord injuries. The approach targets specific cells that normally produce scar tissue after injury, converting them to functional neurons as part of the repair process. Experiments showed that animals receiving the conversion treatment displayed better locomotor performance compared with untreated controls. The study suggests that altering scar‑cell fate can enhance functional recovery after spinal cord damage.

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