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Trial supports MRI surveillance over preventive brain radiation in small-cell lung cancer
Results from the international phase 3 SWOG S1827 MAVERICK trial show that brain MRI surveillance alone improved cognitive failure-free survival compared with MRI surveillance plus prophylactic cranial irradiation (PCI) in patients with…
AI Summary
The phase 3 SWOG S1827 MAVERICK trial found that patients with small‑cell lung cancer who received brain MRI surveillance alone had longer cognitive failure‑free survival than those who also received prophylactic cranial irradiation. The results were presented at the IASLC 2026 World Conference on Lung Cancer, supporting MRI‑only monitoring as the new standard of care for SCLC.
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