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Small-molecule switches put therapeutic CRISPR editing under on-demand control in living tissues
In a study published in Science Translational Medicine, a team of researchers led by Dr.
Summary
In a study published in Science Translational Medicine, a team of researchers led by Dr. Wang Yu from the Shenzhen Institutes of Advanced Technology of the Chinese Academy of Sciences developed PRINCE and Little Prince, dual small-molecule-controlled genome editing systems that allow CRISPR activity to be switched on by drug inducers and kept largely silent in their absence.
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