RNA therapy may help preserve muscle during GLP-1 weight loss | HappeningNow.news

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RNA therapy may help preserve muscle during GLP-1 weight loss

GLP-1 drugs have revolutionized obesity treatment, but they can lead people to lose muscle mass along with fat. And when patients stop treatment, they often regain their weight—primarily as fat.

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GLP‑1 medications have transformed obesity treatment but can cause patients to lose muscle mass as well as fat, and many regain weight—mostly as fat—after stopping the drugs. Researchers at Northwestern University have developed an experimental RNA therapy that prompts the body to burn more calories. In pre‑clinical testing, the therapy amplified the weight‑loss effects of GLP‑1 drugs, suggesting a way to preserve muscle while enhancing overall outcomes.

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