AI Summary

Researchers at The University of Texas MD Anderson Cancer Center discovered a previously unknown pathway that prostate tumors exploit to suppress the immune system by reshaping the tumor microenvironment, making the cancer more resistant to treatment. In preclinical models of castration‑resistant prostate cancer, a combined targeted‑therapy regimen that blocks this pathway enhanced antitumor responses and extended survival. The findings suggest that disrupting the pathway could improve therapeutic outcomes for aggressive prostate cancers.

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