AI Summary

A review of six trials involving almost 800,000 men found that prostate‑specific antigen (PSA) blood‑test screening cuts prostate cancer deaths by two per 1,000 screened, implying that 500 men need to be screened to prevent one death. The analysis describes the benefit as “absolute” and modest, noting that many screened men may undergo unnecessary treatment and associated medical complications. The study is presented as the most comprehensive assessment of PSA screening to date.

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