Summary

Researchers at the University of Houston's College of Pharmacy have discovered an unexpectedly simple strategy to improve the performance of mRNA vaccines and gene therapeutics: adding salt. The findings, published in Small , address one of the biggest challenges facing modern gene medicine—getting fragile therapeutic material to the right place inside cells. "We are introducing salt-loaded lipid nanoparticles as a novel and broadly applicable design principle for gene delivery," said Fanfei Meng, assistant professor and Presidential Frontier Faculty member in the Department of Pharmacological and Pharmaceutical Sciences.

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