AI Summary

Researchers at Penn State have identified a protein complex that acts as a suppressor of transposable elements, the “jumping genes” that make up about half of the human genome. The study, published in the Journal of Biological Chemistry, shows that this complex prevents the elements from copying and inserting themselves elsewhere in the DNA. By limiting these movements, the complex helps maintain genomic stability and reduces the risk of mutations linked to neurodevelopmental disorders, autoimmune disease, and cancer. The discovery adds a new layer to understanding how the genome protects itself from potentially harmful transposition events.

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