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Higher vitamin B12 levels in both parents associated with a lower risk of birth defects
A prospective cohort study quantifying the associations of parental vitamin B12 and red blood cell (RBC) folate with birth defects found that higher parental vitamin B12 before conception and higher maternal RBC folate concentrations…
AI Summary
Researchers analyzing the Shanghai Preconception Cohort found that higher vitamin B12 levels in both mothers and fathers around conception were linked to a reduced risk of birth defects. The study examined blood samples from 3,032 couples taken within four months before conception and compared them with data from 17,765 women tested up to four months into pregnancy. Results were published in the Annals of Internal Medicine, highlighting the potential importance of parental nutritional status at the earliest stages of pregnancy.
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