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CDK1 protein offers clues to which breast cancers will resist targeted therapy
Researchers at the Garvan Institute of Medical Research have discovered that the activity of a protein called CDK1 in breast cancers is linked to how they respond to a common therapy—an insight that could inform more personalized…
Summary
Researchers at the Garvan Institute of Medical Research have discovered that the activity of a protein called CDK1 in breast cancers is linked to how they respond to a common therapy—an insight that could inform more personalized treatment approaches for patients. The study , published in Advanced Science , looked at estrogen receptor-positive (ER+) breast cancer—the most common type, fueled by the hormone estrogen. Many people with this cancer now receive drugs called CDK4/6 inhibitors alongside hormone therapy.
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