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Beyond B cells: Rituximab response may reveal which kidney disease patients can stop steroids
Nephrotic syndrome is caused when the filtering system in the kidneys is damaged, allowing large amounts of protein to leak into the urine.
Summary
Nephrotic syndrome is caused when the filtering system in the kidneys is damaged, allowing large amounts of protein to leak into the urine. It is usually treated with steroids, but in some cases, steroids alone are insufficient, and long-term steroid use has serious side effects. Some patients develop a difficult-to-treat form of the disease that returns when the steroid dose is reduced.
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