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Bacteria that can make testosterone: What could that mean for prostate cancer?
Many prostate cancers depend on androgen hormones, including testosterone, to grow. That is why treatments for advanced disease often try to reduce testosterone production or block its effects.
AI Summary
Scientists have discovered a bacterium in the human urinary tract that can convert the steroid precursor DHEA into testosterone in laboratory conditions. The finding is notable because many prostate cancers rely on androgen hormones, such as testosterone, to grow. Treatments for advanced prostate cancer typically aim to lower testosterone production or block its effects. The bacterial conversion of DHEA to testosterone suggests a previously unrecognized source of androgens that could influence prostate cancer progression.
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