Adding abiraterone to ADT and docetaxel improves survival in… | HappeningNow.news

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Adding abiraterone to ADT and docetaxel improves survival in metastatic prostate cancer

Adding abiraterone to standard treatment provides a lasting survival benefit for men whose prostate cancer has already spread at diagnosis, reinforcing the value of early treatment intensification.

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The PEACE‑1 phase 3 trial, followed for almost eight years, showed that adding abiraterone to standard androgen deprivation therapy (ADT) gives a lasting survival benefit for men diagnosed with de‑novo metastatic castration‑sensitive prostate cancer (mCSPC). The study compared two doublet regimens: ADT plus docetaxel chemotherapy and ADT plus abiraterone. Results from the ESMO 2026 presentation found no significant difference in overall survival between the two combinations, supporting early treatment intensification with either option.

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