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Early cranial radiotherapy may improve outcomes for patients with EGFR-mutant NSCLC and limited brain metastases
Early cranial stereotactic radiotherapy (SRT) administered with first-line osimertinib was associated with improved intracranial control and survival outcomes in patients with EGFR-mutant non-small cell lung cancer (NSCLC) and limited…
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A retrospective analysis of patients with EGFR‑mutant non‑small cell lung cancer and limited brain metastases found that adding early cranial stereotactic radiotherapy (SRT) to first‑line osimertinib improved intracranial disease control and overall survival compared with osimertinib alone. The study compared outcomes for those receiving the combined approach versus osimertinib monotherapy. Results were presented at the International Association for the Study of Lung Cancer 2026 World Conference on Lung Cancer.
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