AI Summary

Researchers at the University of Toronto have built a multi‑organ‑on‑a‑chip system to explore why the heart rarely hosts cancer metastases. The platform links engineered liver and cardiac tissues, allowing direct comparison of tumor cell behavior in a controlled lab environment. When aggressive breast cancer cells were introduced, they readily invaded the liver tissue but displayed markedly lower invasion into the cardiac tissue. The findings suggest intrinsic properties of heart tissue may impede metastatic spread, offering a new experimental avenue for studying metastasis prevention and for testing anti‑cancer drugs.

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