Science · 3 views
Spatial genomics tool maps long-range DNA interactions while preserving cells' locations within tissues
DNA is not randomly distributed within the nucleus but is packaged with proteins into chromatin, which is precisely folded into complex three-dimensional structures.
Summary
DNA is not randomly distributed within the nucleus but is packaged with proteins into chromatin, which is precisely folded into complex three-dimensional structures. However, scientists have not fully understood how this complex three-dimensional (3D) organization is regulated or how it changes over time.
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