AI Summary

Researchers at Boston Children’s Hospital reported in Nature that a single mutated gene can trigger changes across an entire network of genes linked to autism, suggesting a mechanism for why diverse mutations in many autism‑associated genes produce similar outcomes. Their analysis highlighted the gene ZFX as a pivotal factor in the well‑documented female protective effect, wherein females carrying autism‑related mutations often exhibit milder symptoms. The study proposes that ZFX’s central role may underlie this sex‑based resilience.

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