AI Summary

Researchers have created a standardized workflow for analyzing DNA methylation in single cells. The protocol pairs an improved laboratory procedure with an automated data‑analysis tool, simplifying the study of cell‑to‑cell variation. Published in *Nature Protocols*, the work was led by scientists at the Institute of Health and Medical Technology, Hefei Institutes of Physical Science, Chinese Academy of Sciences. DNA methylation regulates gene activity and influences cell development and disease. Traditional sequencing averages methylation across many cells, masking individual differences; the new single‑cell method overcomes the challenge of limited DNA per cell.

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