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Protein-building RNA molecules reveal possible remnants of an ancestral genetic code
The genetic code determines the correspondence between genetic instructions and amino acids—the building blocks that form proteins. How this correspondence arose is one of the major open questions in evolutionary biology.
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A study led by Dr. Lluís Ribas de Pouplana, an ICREA researcher at IRB Barcelona, reports the discovery of RNA molecules that can build proteins and appear to retain features of an ancient genetic code. The findings address how the modern correspondence between nucleic‑acid sequences and amino acids may have originated. By analyzing these protein‑building RNAs, the researchers identified patterns suggesting remnants of a primordial coding system. The work provides new insight into one of evolutionary biology’s major unanswered questions.
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