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People with atrial fibrillation at intermediate risk of stroke benefit from oral anticoagulants, clinical trial finds
Patients with atrial fibrillation (AF) are at increased risk of stroke. ESC Guidelines recommend oral anticoagulants for patients with AF at high risk of stroke with a Class I recommendation.
AI Summary
A clinical trial called SINGLE‑AF found that oral anticoagulant therapy reduced the risk of adverse clinical events compared with no anticoagulation in patients with atrial fibrillation who have an intermediate risk of stroke. The results were presented during a Hot Line session at the ESC Congress 2026 and were published simultaneously in the New England Journal of Medicine.
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