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Pausing certain arthritis drugs after COVID-19 vaccination raises flare risk without improving antibody response
For patients with inflammatory arthritis, holding certain disease-modifying antirheumatic drugs (DMARDs), namely select biologic or Janus kinase inhibitor (JAKi) therapies, for two weeks at the time of a supplemental COVID-19 vaccine dose…
AI Summary
A study published online on Oct. 5 in JAMA Internal Medicine found that patients with inflammatory arthritis who pause certain disease‑modifying antirheumatic drugs—specifically selected biologic agents or Janus kinase inhibitors—for two weeks around a supplemental COVID‑19 vaccine dose do not see an improvement in humoral immune response. The research examined the effect of this pause on antibody production following the vaccine. The findings suggest that withholding these therapies does not enhance vaccine‑induced antibody levels.
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