AI Summary

Research led by pathology professor Mikhail Nikiforov, Ph.D., identified a mechanism that enables cancer cells to spread to the brain, suggesting a potential new therapeutic target. The findings appear in Cell Reports under the title “SERINC2‑mediated phosphatidylserine remodeling activates protrusion‑localized AXL signaling to promote brain metastasis.” The study examined how tumor cells acquire migratory and invasive abilities that allow them to form new tumors within the brain. Brain metastases are described as one of the most difficult cancer complications, often resulting in poor outcomes and limited treatment options.

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