Summary

Inflammation of lymphatic vessels, which drain brain waste, may be involved in the onset of Parkinson’s disease. The condition is associated with the build-up of a misfolded protein called alpha-synuclein, which may not be efficiently removed from the brain if the lymphatic vessels are impaired. But the accumulation of alpha-synuclein seems to further damage these vessels, creating a self-reinforcing chain of events where each problem worsens the other. “It is a vicious cycle,” says Justin Rustenhoven at the University of Auckland in New Zealand.

AI summaries can be wrong sometimes—always verify important details using the source article.