Summary

Vape devices are flooding teens' bodies with increasingly heavy doses of addictive nicotine, a new study finds. Average urine levels of a key nicotine metabolite, cotinine, nearly tripled among teenagers over a period of a few months in late 2024, researchers report in JAMA Psychiatry . Teens' cotinine levels appeared to rise along with the evolution of e-cigarettes. As the researchers explained, newer pod-based vape devices carry higher-concentration nicotine salts, while disposable devices feature larger-capacity tanks.

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