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Newly discovered pathway fuels production of cancer-driving proteins
A previously unknown mechanism helps cancer cells selectively produce proteins that drive tumor growth—such as KRAS—in common cancers, according to new research from The University of Texas MD Anderson Cancer Center.
AI Summary
Researchers at the University of Texas MD Anderson Cancer Center discovered a previously unknown mechanism that allows cancer cells to selectively produce proteins that drive tumor growth, such as KRAS, in common cancers. The study, published in *Nature Cell Biology*, shows that this mechanism involves a specific enzyme that could be targeted to improve responses to existing targeted therapies. By inhibiting the enzyme, scientists believe it may help overcome resistance that often develops during treatment. The research was co‑led by Pawel Mazur, Ph.D., associate professor of experimental radiation oncology, with collaborators from other institutions.
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