AI Summary

Researchers have developed a new tool designed to identify problematic clinical trials before they are included in systematic reviews. The tool flags studies that may contain human error or research misconduct, which can distort the evidence base that informs treatment guidelines. An example cited was a systematic review of ivermectin for COVID‑19, where some trials used were later found to be non‑authentic by health authorities in the U.S., U.K., and EU. Subsequent high‑quality trials showed little or no benefit of ivermectin, underscoring the risk of basing recommendations on flawed data.

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