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Neural signaling protein could be therapeutic target for autism-linked gene deletion

A particular signaling protein in the brain could be a therapeutic target for neurological disorders arising from the deletion of the autism-linked gene MEF2C, University of Illinois Urbana-Champaign researchers found in a new mouse study…

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University of Illinois Urbana‑Champaign researchers identified a specific brain signaling protein as a potential therapeutic target for disorders caused by deletion of the autism‑linked gene MEF2C. The finding comes from a mouse study that examined how loss of MEF2C contributes to neurological and developmental conditions such as autism, epilepsy and Alzheimer’s disease. The work, led by professor Nien‑Pei Tsai, was published in the Proceedings of the National Academy of Sciences.

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