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Nanoneedle arrays map RNA in fresh tissue without sequencing or amplification
Recently, spatial omics has become a powerful tool, enabling researchers to see not only what molecules are present in a tissue, but also where they are located and how they are organized across cells, tissue structures and local…
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Researchers highlight that spatial omics technologies, which map molecules within tissues, have advanced cancer, neurobiology, and immunology studies by revealing molecular locations and organization. However, many of these methods require costly instruments, sequencing, complex tissue preparation, long workflows, and heavy computational resources. While such demands are acceptable in well‑equipped research labs, they pose significant barriers in pathology settings where rapid biopsy analysis, clinical practicality, and wide patient access are essential. The article questions how many spatial omics tools are ready for routine clinical use.
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