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'Monday Night Football' prediction, odds, time: Broncos vs. Chiefs picks by expert on 32-15 run
After missing the postseason for the first time in over a decade, the Kansas City Chiefs look to return to form when they kick off their 2025 season against the defending AFC West champion Denver Broncos on Monday Night Football.
AI Summary
The Kansas City Chiefs open their 2025 season on Monday Night Football against the defending AFC West champion Denver Broncos. The matchup, scheduled for 8:15 p.m. ET at GEHA Field at Arrowhead Stadium in Kansas City, marks the return of quarterback Patrick Mahomes after missing the end of last season with a torn ACL and MCL. Kansas City enters as a 2.5‑point favorite, with the over/under set at 42.5 total points, one point lower than the season opener. The Chiefs finished 2025 at 6‑11 overall, while the Broncos posted a 14‑3 record.
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