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Little-known protein offers a potential target for treating Chagas disease
In Brazil, researchers at the University of São Paulo (USP) and their collaborators have identified a promising target for developing new Chagas disease treatments.
Summary
In Brazil, researchers at the University of São Paulo (USP) and their collaborators have identified a promising target for developing new Chagas disease treatments. In laboratory tests, the group succeeded in interrupting the infection cycle of the Trypanosoma cruzi parasite by reducing the production of one of its proteins. Without adequate levels of this molecule, the pathogen lost its ability to differentiate into its infectious form within human heart cells, severely impairing its development. The discovery was detailed in an article published in August in the journal Communications Biology .
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