AI Summary

Scientists at the Broad Institute’s Center for Human Brain Variation mapped previously unseen cellular architecture in the striatum, a brain region linked to decision‑making, movement, and disorders such as addiction and neurodegeneration. The study identified six distinct zones within the striatum based on gene‑expression patterns. It also showed that the boundaries between these zones become less defined as people age, and that both aging and genetic variation influence gene expression in this area. The findings are part of a larger BRAIN Initiative Cell Atlas Network effort to create a detailed cellular map of the human brain.

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