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Jawbone necrosis in advanced breast cancer: Study highlights the importance of oral health
Antiresorptive drugs, which reduce bone breakdown, are an important part of treatment for breast cancer that has spread to the bones.
Summary
Antiresorptive drugs, which reduce bone breakdown, are an important part of treatment for breast cancer that has spread to the bones. However, their use can be associated with medication-related osteonecrosis of the jaw (MRONJ), a condition in which bone tissue in the jaw dies. In a Finnish registry study, osteonecrosis of the jaw was diagnosed in 12.6% of patients treated with denosumab during long-term follow-up.
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