AI Summary

Researchers at the University of Texas MD Anderson Cancer Center found that T cells can eliminate acute myeloid leukemia (AML) cells through a previously unknown pathway. The study, published in PNAS, was led by Cassian Yee, M.D., and Kapil Saxena, M.D. It shows that AML cells, which normally lack the machinery for T‑cell recognition, instead rely on the CD64 protein and an intact T‑cell receptor (TCR) to trigger an immune attack. This discovery may explain AML’s sensitivity to immune‑based therapies and could inform future cancer immunotherapy development.

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