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How common dietary fats can aggravate chronic itch
A team of researchers has found that a breakdown product from a commonly consumed fat can bind to a receptor associated with psoriatic itch and inflammation.
AI Summary
Researchers discovered that a breakdown product of linoleic acid, a common dietary fat, can bind to a receptor linked to psoriatic itch and inflammation. In a mouse model, blocking this receptor reduced itch symptoms. The study, published in Communications Biology, highlights how diet may influence chronic itch triggers. It suggests that targeting this pathway could lead to new treatments for psoriasis and atopic dermatitis. Linoleic acid is naturally present in nuts, seeds, and vegetable oils, and while needed in small amounts, excess intake is linked to heart disease and diabetes.
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