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How blood vessels distinguish between growth and inflammation
The angiopoietin-Tie signaling pathway has long been known to be essential for the maturation and maintenance of healthy blood vessels. It stabilizes the vessel wall and regulates vascular growth during development.
AI Summary
The angiopoietin‑Tie signaling pathway is crucial for blood vessel maturation and maintenance, stabilizing vessel walls and regulating vascular growth during development. It also contributes to inflammation by activating vessels and allowing immune cells to exit the bloodstream and enter surrounding tissue. The dual role of this pathway in both growth and inflammatory processes has been recognized, but the mechanisms that enable it to perform these distinct functions remain unclear.
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