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High lung pressure may protect newborns with diaphragmatic hernia from blood congestion
Brazilian research published in the journal Scientific Reports sheds light on the rapid and often fatal deterioration in the health of newborns with congenital diaphragmatic hernia (CDH).
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Brazilian researchers reported in Scientific Reports that high lung pressure may protect newborns with congenital diaphragmatic hernia (CDH) from sudden blood congestion, a common cause of rapid deterioration. The study identified a biological mechanism linking lung pressure to reduced risk of fatal congestion, challenging current neonatal intensive‑care practices. CDH, a rare defect where an incomplete diaphragm allows abdominal organs to intrude into the chest, compresses developing lungs and impairs their growth. The findings suggest that existing treatments may need reassessment to avoid compromising this protective pressure.
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