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Global survey reveals major variation in the measurement of bone and mineral metabolism biomarkers
Researchers from the International Osteoporosis Foundation (IOF) and International Federation of Clinical Chemistry and Laboratory Medicine (IFCC) Joint Committee on Bone Metabolism published a study examining self-reported practices…
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Researchers from the International Osteoporosis Foundation and the International Federation of Clinical Chemistry and Laboratory Medicine Joint Committee on Bone Metabolism analyzed self‑reported laboratory practices for measuring bone status indices in blood. Their study, published on Aug. 7, 2026 in Clinical Chemistry and Laboratory Medicine, gathered 231 responses from labs in 41 countries. The results reveal substantial global variation in how these biomarkers are measured, which hampers data sharing, test standardization and reduces the clinical impact of the assays.
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