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First ever reported cryo-EM visualization of E. coli TGT structure
The enzyme tRNA-guanine transglycosylase (TGT) chemically modifies transfer RNA (tRNA) and plays a key role in how disease-causing bacteria control the production of proteins needed to cause infection. E.
AI Summary
Researchers have successfully visualized the structure of E. coli's tRNA-guanine transglycosylase (TGT) using cryo-electron microscopy (cryo-EM). This achievement marks the first reported cryo-EM visualization of the E. coli TGT structure. The enzyme TGT plays a crucial role in the production of proteins by disease-causing bacteria, including E. coli and Shigella, which causes shigellosis.
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