EFHD1 may turn fatty liver disease into injury, with inhibition reduc… | HappeningNow.news

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EFHD1 may turn fatty liver disease into injury, with inhibition reducing scarring by up to 60%

Obesity-related metabolic liver disease affects hundreds of millions of people worldwide, but only some of those livers develop scarring, become inflamed and eventually fail.

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Mitochondria (green) are compact and bean-shaped. Chaudhuri Obesity-related metabolic liver disease affects hundreds of millions of people worldwide, but only some of those livers develop scarring, become inflamed and eventually fail. University of Utah researchers have identified a protein, EFHD1, that appears to drive that transition by triggering an out-of-place antiviral immune response.

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