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EFHD1 may turn fatty liver disease into injury, with inhibition reducing scarring by up to 60%
Obesity-related metabolic liver disease affects hundreds of millions of people worldwide, but only some of those livers develop scarring, become inflamed and eventually fail.
Story Brief
Mitochondria (green) are compact and bean-shaped. Chaudhuri Obesity-related metabolic liver disease affects hundreds of millions of people worldwide, but only some of those livers develop scarring, become inflamed and eventually fail. University of Utah researchers have identified a protein, EFHD1, that appears to drive that transition by triggering an out-of-place antiviral immune response.
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