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Children with a common genetic variant may have more inflammation in response to an asthma drug
Children with a variant in the SERPINE1 gene—which is found in 60% of the population—may be less responsive to mepolizumab, a drug used to treat asthma flares, according to a study published in the Journal of Allergy and Clinical…
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A study in the Journal of Allergy and Clinical Immunology found that children carrying a common SERPINE1 gene variant, present in about 60 % of people, may respond less effectively to the asthma flare medication mepolizumab.
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