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Catheter ablation does not improve quality of life related to atrial fibrillation

Lancet (2026). DOI: 10.1016/s0140-6736(26)01558-8 Catheter ablation for atrial fibrillation (AF) did not significantly improve AF-related quality of life compared with a sham procedure, despite reducing AF recurrence.

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Lancet (2026). DOI: 10.1016/s0140-6736(26)01558-8 Catheter ablation for atrial fibrillation (AF) did not significantly improve AF-related quality of life compared with a sham procedure, despite reducing AF recurrence. These were the main findings of the PVI-SHAM-AF trial presented in a Hot Line session at ESC Congress 2026 and published simultaneously in The Lancet. The prevalence of AF is projected to increase substantially due to the aging population and the rise in cardiovascular risk factors.

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