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CAR T-cell therapy bolstered by stiffening up cancer cells first
A therapy that has revolutionised how we treat blood and skin cancers could become even more effective.
Summary
A therapy that has revolutionised how we treat blood and skin cancers could become even more effective. Making cancer cells stiffer bolstered the effects of immunotherapy, when the immune system is manipulated to kill off tumours, in mice with the most serious form of skin cancer. The impressive results have scientists optimistic that a similar approach could improve survival rates in people being treated with immunotherapies like CAR T-cell therapy. “It’s a completely new concept,” says Yi Sui at Queen Mary University of London, who wasn’t involved in the research.
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